Development of Effective Vaccines against Pandemic Influenza
نویسندگان
چکیده
منابع مشابه
Vaccines for Pandemic Influenza
Recent outbreaks of highly pathogenic avian influenza in Asia and associated human infections have led to a heightened level of awareness and preparation for a possible influenza pandemic. Vaccination is the best option by which spread of a pandemic virus could be prevented and severity of disease reduced. Production of live attenuated and inactivated vaccine seed viruses against avian influenz...
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Recent years' enzootic spread of highly pathogenic H5N1 virus among poultry and the many lethal zoonoses in its wake has stimulated basic and applied pandemic vaccine research. The quest for an efficacious, affordable and timely accessible pandemic vaccine has been high on the agenda. When a variant H1N1 strain of swine origin emerged as a pandemic virus, it surprised many, as this subtype is w...
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Genetic vaccine technology has been considerably developed within the last two decades. This cost effective and promising strategy can be applied for therapy of cancers and for curing allergy, chronic and infectious diseases, such as a seasonal and pandemic influenza. Despite numerous advantages, several limitations of this technology reduce its performance and can retard its commercial exploit...
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When WHO’s Strategic Advisory Group of Experts (SAGE) on immunisation met on July 7, 2009, they recognised that pandemic infl uenza A H1N1 vaccines, when they become available, are almost entirely committed under contract to a small number of industrialised countries. SAGE commended WHO for trying to improve real-time access in poor countries, but these eff orts will not have substantial eff ec...
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T he global spread of highly pathogenic H5N1 infl uenza through poultry fl ocks is driving a large research effort aimed at mitigating the worst effects of an eventual human pandemic. Mathematical models and computer simulations are being used to explore different policy options in infl uenza pandemic control (for examples, see [1–4]). In a new study published in PLoS Medicine, Riley, Wu, and L...
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ژورنال
عنوان ژورنال: Immunity
سال: 2006
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2005.12.005